Dr. Joseph E. Ambrose, Jr., of Indiana, PA, passed away at Indiana Regional Medical Center (IMRC), on Tuesday, October 27, 2026.
He was born in Darby, PA, to Joseph E. Ambrose Sr. and Teresa M. Ambrose.
Joe graduated from Lansdale Catholic High School before studying at Philadelphia College of Osteopathic Medicine where he also served his residency at the hospital there.
Eventually he settled in Indiana, PA, where he practiced Internal Medicine for over 30 years. Upon retiring, Joe enjoyed attending his Bible study and rosary groups. He also volunteered at the St. Vincent De Paul thrift store.
To relax he spent time at his camp fishing and kayaking.
Surviving are his wife of 21 years, Paula Ambrose; his children, Joseph Ambrose III (Rebecca), Meredith Ambrose, Cassidy Fairman (Austin). Joe was expecting his first grandchild in November. Also surviving are his four siblings, Teresa, Joan (Tony), Dennis (Josephine), and Greg.
Joe was preceded in death by his parents and brother-in-law, Irvin Stevens.
Special thanks to the following for their kindness and care during this difficult journey: Dr. Amin, Dr. Elias, Dr. Nesper, Dr. Turnbull, and Dr. Walton; IRMC nurses, Abby, Amber, Emily, and Mike; Concordia nurses, Chloe and Kali; and Tim Neal at Colonial Toyota. May God bless each one of you.
In accordance with Joe’s wishes, a visitation will not be held. A Mass of Christian Burial will be celebrated on Friday, November 6, 2026, at 10 AM, at St. Bernard of Clairvaux Roman Catholic Church, 200 Clairvaux Drive, Indiana, PA, with Father Richard N. Owens, O.F.M., Cap as celebrant. Entombment to follow in St. Bernard Cemetery Mausoleum.
In lieu of flowers, please consider donating to Lifesteps Family Caring Fund, (please denote Indiana County on the memo line) 383 New Castle Road, Butler, PA 16001.
To share a memory or send an online condolence, please visit www.donahuetylinski.com
